I have 4 Harmony Hubs. For that room, I have a Projector and TV alone with two AVRs, sound-bar, bass shakers for my chairs, sub woofers, etc…So the Harmony Hub is essential for changing all the necessary inputs and ST for turning on/off stuff all built into the Routine.
In that room, the PS3 is used strictly as a BD Player and works with the Harmony Via Bluetooth. Two of my family members have PS4s for gaming but Harmony didn’t work with them or the Nintendo Switch.
I haven’t tried it myself but there is a DTH for the PS4 now.