The following is based on how Tado works which is not a Z-Wave system. However logically other systems should work the same way.
Tado sell both a Smart Thermostat and matching smart TRVs. If any single one of them calls for heat this causes the boiler to provide heat. If the Smart Thermostat is in a room with a radiator which does not have a smart TRV then that radiator would of course receive heat. Other radiators equipped with smart TRVs would locally decide whether to shut off or not based on their target temperature setting.
The best solution is to ensure every radiator has a smart TRV including the one in the same room as the main smart Thermostat. If the smart Thermostat is then in the same room as a smart TRV with Tado you can link them so the smart Thermostat sensor overrides the thermostat sensor in the smart TRV and acts as the external temperature sensor for that TRV.
The result will be if a single room calls for heat via its smart TRV the boiler fires up, all other rooms would have their radiators shut off by their smart TRVs and heat goes to just the single room calling for heat.
Similarly Tado support multi zone configurations using multiple smart Thermostats. This would enable supporting an underfloor zone.
There is a 3rd party app for Tado for Smartthings. Tado do allow setting the target temp of each smart Thermostat and TRV independently and do allow setting ‘off-sets’ to compensate for local room conditions that might be distorting temperature readings.