The short answer is yes, using virtual devices and Alexa routines (not smartthings routines— the ones you set up in the Alexa app.)
But the functionality is limited and the long explanation is really long and to be honest, I just got out of hospital last week and I’m too tired to go into all the details. 
here’s the community FAQ that explains how it works. If you have any questions about it after reading that, hopefully others will be able to help you.
FAQ: Can I trigger an Echo Action without Speaking to It?
You can do something similar with Siri Shortcuts, same issues.