Yes you can. Local control from Hub to device is what Hubitat gives you. Right now you have 2 to 3 cloud servers that must all be working to control devices. With Hubitat, you often would just have one needed. Google or Amazon. When you use Alexa, commands go to the cloud, but execution of the task is local.
To control with a pico, you don’t even need Internet, which isn’t the case with the ST/Node.js setup.