Nothing that works out of the box with identical functionality in a mains-operated device that also controls a single fixture manually, as the Insteon keypad on/off button does.
There are quite a few alternative devices which meet many of the same use cases, so it really depends on exactly what you were looking for.
The 21st century way to do this type of function is just with a “dashboard,” either on a tablet or an inexpensive WiFi phone. A lot of people use these.
There is a very popular third-party app, action tiles, which has a license fee of about $30 per hub (not per tablet). You can select exactly which devices you want to appear on each tablet.
And then a typical WiFi phone costs under $20 at Walmart. So that’s one popular option.
Then there are a couple of multibutton mains-powered Z wave devices that are also popular. These are very similar to the Insteon devices except they don’t have as many buttons and they don’t control an individual relay from the switchbox – – everything is wireless. And you have to print your own labels. They do replace an existing light switch, they just don’t physically control the relay that was there.
Then there are a number of different batterypowered multibutton devices. One of the most popular from remotec costs around $49, and has eight buttons, each of which can do tap, double tap, or long hold, giving you 24 total functions.
You can find all of the button devices, both battery powered and mains powered, described in the buttons FAQ ( this is a clickable link)
Finally, if you really want custom engraving, there is a way to get Lutron Picos to work with smartthings, but it requires using an additional device as a “man in the middle” server and you have to use a community integration, not the official one. But the picos themselves are very inexpensive, typically under $20, and come in several different styles. But this is technically the most difficult to set up because while there is an official SmartThings/Lutron integration, normally the Picos are invisible to smartthings.
So as you can see, there are a number of different options, but nothing which matches the features of the Insteon keypads exactly, so it just depends on what you need.